Nanyang Technological University in Singapore has developed a way to selectively target and destroy brain tumor cells using extremely low-dose X-rays. Radiodynamic therapy stopped tumor development and doubled survival time in mice without damaging healthy cells. It employs a unique substance known as a “molecular radio afterglow dynamic probe” (MRAP) composed of biochemicals and iodine. These probes are inserted directly into the tumor and activated by low-dose X-rays, producing near-infrared afterglow and cancer-destroying free radicals and leaving healthy cells unharmed. The team intends to continue testing the safety and efficacy of MRAPs in bigger preclinical models before moving on to human trials.

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