An innovative approach to protecting African children from malaria could reduce deaths and illness by 70 percent in the African Sahel. Researchers who studied 6,000 children aged under 17 months in Burkina Faso and Mali found that, over three years, three doses of the vaccine and drugs before the worst malaria season, followed by a booster dose before subsequent rainy seasons, controlled infections much better than vaccines or drugs alone. The vaccine kills parasites that multiply in the liver, while anti-malarial drugs target parasites in the body's red blood cells.

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